Genetic testing for breast and ovarian cancer australia
Back to test list. A proportion of individuals with a diagnosis or family history of breast or ovarian cancer have a familial predisposition to develop these cancers due to variants in any one of several genes. The purpose of testing these genes can be categorised as follows:. Variants in these genes can potentially cause breast or ovarian cancer, or both, and a variety of others cancers. In particular, the expanded panel is only suitable for requestors familiar with the management considerations arising from identification of a variant in any of these genes. The identification of a pathogenic variant in one of these genes in an affected person can explain the personal and family history of cancers.
RIS file. Genetic testing is available in specialised laboratories, but is expensive and presents a significant technical and interpretative challenge. Identification of a causative mutation carries lifelong health and psychosocial implications for the woman and her relatives. It also influences surveillance and treatment options. Testing should therefore only be considered with professional genetic counselling by specialists in familial cancer clinics. Breast cancer is the most common form of cancer among women in Australia.
Genetic testing may be offered by a specialist or consultant physician for a person with breast or ovarian cancer who meets certain criteria. The criteria for testing take several factors into consideration, such as the age at which the cancer was diagnosed, specific characteristics of the cancer, and whether other close family members have also been diagnosed with certain types of cancer previously. Genetic testing of an unaffected person is generally not performed unless a specific genetic fault pathogenic variant has already been identified in a family member.
If you have already entered your email address and created a password while completing a form within our site, it is likely you have an account. You should have received an email to confirm this. Find out more about genetic testing for women diagnosed with ovarian cancer, and implications for treatment.