METHODS: A retrospective review was conducted of the medical records of seven patients with radiologically documented sinus tracts after restorative proctocolectomy or low rectal anastomosis was managed with fibrin glue obliteration of the tract. The sinus was gently debrided with a curette and then filled with fibrin glue. Postoperatively, the patients received metronidazole 1. Outpatient examination of the internal opening was performed at 1, 3, and 12 weeks postoperatively.
Fibrin Glue Treatment of Low Rectal and Pouch-Anal Anastomotic Sinuses | SpringerLink
Purpose: The aim of this study was to evaluate the long-term success and complication rate of fibrin-glue treatment of anal fistulas. Methods: Patients with an anal fistula presenting to a single surgeon over a three-year period were enrolled in this study. At their first operation, all 48 patients years old underwent anoscopy, biopsy, destruction of the internal gland, and placement of a draining seton. Approximately two months later after preoperative bowel preparation, the seton was removed, the internal opening closed with a single suture, and fibrin glue instilled by way of the external opening to seal the fistula tract. Patients were followed closely to document the results of treatment and any complications. Long-term follow-up was done by telephone interview. Results: Cause of the anal fistula was cryptoglandular in 36 75 percent patients, Crohn's disease in 5 10 percent , and miscellaneous in 7 15 percent.
Fibrin Glue Treatment of Low Rectal and Pouch-Anal Anastomotic Sinuses
Treatment of fistula-in-ano with cyanoacrylate glue with and without prior seton placement in rats 1. Acquisition, interpretation and analysis of data. Conception and design of the study, interpretation of data, manuscript writing, critical revision. Technical procedures, acquisition of data.
New sphincter-saving approaches have been applied in the treatment of perianal fistula in order to avoid the risk of fecal incontinence. Among them, the fibrin glue technique is popular because of its simplicity and repeatability. The aim of this review is to compare the fibrin glue application to surgery alone, considering the healing and complication rates. We performed a systematic review searching for published randomized and controlled clinical trials without any language restriction by using electronic databases. All these studies were assessed as to whether they compared conventional surgical treatment versus fibrin glue treatment in patients with anal fistulas, in order to establish both the efficacy and safety of each treatment.